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Why Is It Difficult For Antibodies to Fight AIDS?

The primary target for HIV is the ENV glycoprotein. This head protein interacts with the T-cell receptor CD4 which is how HIV enters its target cell.





As a glycoprotein, it has numerous sugars on the outside surface. Those sugars protect the head protein. ENV itself is broken up into two portions, the GP120 and the GP41 domains. The bottom figure shows the sequence conservation of the GP120 protein. In green are the sugars. In white are the conserved domains and in purple are the more variable domains. As it can be seen, when the protein is in its closed state, the headgroup is protected by sugars. The exposed protein domains are the most variable portions of the protein.

Liverpool Destroys Huddersfield To Get Back To The Top Of The Table

Liverpool go back to the top of the table, for the next 42 hours at least, with the expected Friday-night stroll. Naby Keita gave them the lead after 15 seconds, and Sadio Mane and Mo Salah scored two apiece in a painfully one-sided match. 

Liverpool will now become Burnley fans for the weekend before turning their attention to Barcelona on Wednesday.


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Bad News For Manchester City Despite Beating Manchester United At Old Trafford - See Details

Manchester City took the driving seat on the Premier League table as they displace Liverpool form the top spot after their 2-0 win over their City rivals Manchester United at the Old Trafford. Despite the fact that Cityzens fans should be in a celebratory mood but this joy has been cut short after the news concerning one of their most important players who got injured in the game.

Manchester City midfielder Fernandinho is unsure of the severity of his knee injury as he prepares to undergo a scan on Thursday. The midfielder is set to have a scan on the injury he suffered in the derby win over United. The Brazil international, 33, came off in the second half of City’s 2-0 derby win over Manchester United that returned them to the top of the Premier League table.


Already without the injured Kevin De Bruyne, City could now lose Fernandinho with four games remaining in their season. Fernandinho said he would have to wait for the results of a scan to know the severity of the injury scare…

Reports: Real Madrid Star Threatens To Quit If His Jersey Is Given To Eden Hazard

    After a dismal season, it seems that Real Madrid are ready to give everything in the transfer market to land all their major targets. And on top of that list of targets is the name of Eden Hazard.

The Chelsea winger is believed to be very close to a move to Real Madrid with Zinedine Zidane and Florentino Perez trying to close the deal as quickly as possible. Therefore, they are reportedly willing to accept any demands from Chelsea and Hazard.

According to DiarioGol, Hazard is expected to ask for the number 10 jersey at Madrid, which current Ballon d’Or holder Luka Modric dons. The report adds that the Madrid midfielder has been made aware of the possibility of giving up his shirt number which he hasn’t taken lightly.

     Modric is even ready to lower his wages in order to get a move to Inter in the summer transfer window if he’s asked to give up the number 10 jersey. 

FOX Sports Probability Rating: 1/5 – This one’s a highly speculative report from DiarioGol and it’s highly unlikely t…

Bad News For Chelsea Despite Qualifying For Europa League Semi-Final

Chelsea progressed to semi-final after defeating Slavia Prague in a seven-goal thriller, but fans of the club will not be happy as latest report says Real Madrid are to finalise the move for the Blues talisman Eden Hazard ‘in coming days’ as they prepare to announce Belgian as third summer signing ahead of next season.


     Real Madrid are close to capturing Chelsea star Eden Hazard as their third signing before next season, according to Marca. The Belgian’s signature was one of Zinedine Zidane’s first requests upon returning to the Bernabeu as coach 10 months after leaving.


     Hazard would become the club’s third signing before the new season, after the arrivals of defender Eder Militao and Brazilian wonderkid Rodrygo Goes. The deal is set to cost Real Madrid around £85million, with Hazard entering the final year of his contract and having stated his desire to leave the Premier League.

     These are the first signs of Los Blancos’ planned rebuild after a disappointing season…

'One doesn't win by chance' - Allegri slams criticism after Juve's eighth successive Serie A title

The Turin club claimed their their fifth Scudetto under their current manager and he insisted the job of winning the title is harder than it seems.

     Juventus head coach Massimiliano Allegri said success does not come by chance after guiding the Italian giants to an eighth successive Serie A title.

     Saturday's 2-1 victory over Fiorentina extended Juve's domestic dominance with five rounds remaining – a streak dating back to 2011.

     Allegri has claimed five successive Scudetto honours since replacing Antonio Conte in 2014, however, he has been criticised for Juve's failure in Europe.

     Juve – who have finished runners-up in the Champions League twice under Allegri amid their drought which goes back to 1996 – were eliminated by Ajax in the quarter-finals this season.

     Discussing his critics, Allegri told reporters: "That's part of the game and it has to be accepted because it could also be stimulating.

     "What I say, well rather than s…

Healing From An Emotionally Abusive Relationship

The thing with emotional abuse is that it takes long for the victim to recognize that they were or are being emotionally abused. You cannot heal from a condition you are not even aware you are suffering from. Sometimes even the abusers themselves are not aware that their behavior is tantamount to abuse.

     For those that are aware of their behavior, they do their best to ensure that the person abused remains under their control. They will manipulate them by taking them to extremes of highs and lows. One day they are exceptionally good to you and the next day they are the complete opposite. This confuses the victim and makes it even harder for them to walk away from such a relationship.

     Survivors of emotionally abusive relationships are mostly left with low self-esteem. They have a tough time trusting people again. If you’ve been in such a relationship, you might have experienced months or years feeling unworthy and unappreciated.

     Nothing you ever did was good enough. You …

Semi-Final Fixtures For Europa League Confirmed

Following the conclusion of the quarter-final ties in the ongoing Europa League which were concluded on Thursday night, organisers of the competition have confirmed the fixtures for the semi-final matches which will be played on May 2 and 9.

      Arsenal tutored by Unai Emery which qualified for the semis after defeating Napoli 1-0 in Italy a weeks after the Gunners had won the first leg 2-0 at the Emirates will now face Spanish side Valencia, who saw off Villarreal 2-0 on the night and 5-1 on aggregate.

      London rivals, Chelsea which survived a scare from Slavia Prague to win 4-3 at Stamford Bridge and progressed 5-3 on aggregate in the quarterfinals will now take on German side Frankfurt which scaled through on away goals after losing 4-2 at Benfica, but claimed a 2-0 win at home.

      The fixtures for the semi-finals which features two English teams, one Spanish team and a German side will begin on May 2 and 9, while the final is set to be staged in the city of Baku on …

Cute Couple Do Doggy Pose As They Rock Matching Outfits In Pre-Wedding Photos

An excited Nigerian couple do a doggy pose as they rock matching outfits in their pre-wedding photoshoot. The couples who shared the photo on social media has gotting alot of people talking. Wishing the couple happy married life in advance.


     We are sure that a pre-wedding love story is always a great idea. But how do you choose the right concept, pick up clothes and determine the venue of the shoot? Tips on how to go about pre wedding photos.


     If you are looking for appropriate ideas of your pre-wedding shoot, you can take a look at Bella Naija’s wedding section and get inspired by images created by the best professional photographers and studios.


     Almost every pre-wedding photo session has several locations. Most of the shots were taken in studios using various decorations. Besides, there are a lot of pictures outdoors with nature.


     The shoot location largely determines the photo shoot style and its future result. The location should not be only beautiful but al…

Mohamed Salah Explains His Goal celebration After Stunning Strike For Liverpool In Chelsea Win

The Liverpool star adopted a yoga style pose after his incredible goal to make it 2-0 to Liverpool against Chelsea at Anfield.

     Mohamed Salah has explained the celebration after his stunning strike in Liverpool's 2-0 win against Chelsea.

     The Reds took all three points and moved back to the top of the Premier League table after today's crunch clash at Anfield.

     Sadio Mane opened the scoring, before Salah struck a thunderbolt to put the game beyond the visitors.

     He by adopting a yoga-style pose before being mobbed by his team-mates.

     Speaking on Sky Sports after the match he said: "I am a yoga man!"


     I do yoga and it just came into my mind."

     Asked about his goal, Salah added: "I don't think. I just feel."

     This one I decided, because it was far, to hit it with power."

      Jamie Redknapp put it to him that it might have been his best goal yet for Liverpool.

     But Salah said the strikes against Everton…

Two Bodies Found Dumped in Migori

Police in Migori are looking for relatives of two men whose bodies were found dumped in different spots. One was retrieved on Monday after residents spotted it floating on River Migori. 

     “Police and members of the public pulled the body, which was that of a man aged about 35 years, from the water, said local Police Commander Joseph Nthenge. 

      The police report indicated that the body did not have injuries. However, Victor Owino, a witness, said it had deep wounds on the neck.

      Elsewhere in Kuria East, a driver of a grader is said to have crushed an unidentified man believed to have been drunk and lying on the roadside.

      Mr Nthenge invited the public to help identify the corpses.


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16 Years Old And 15 Years Old Girlfriend Set To Tie The Knot

A young South African couple have got tongues wagging due to their tender age.

     The 16-year-old son of a bishop is set to tie the knot with his 15-year-old girlfriend

     The 59-year-old bishop is fully in support of the union as he even took it upon himself to pay the bride price

      Falling in love can happen to anyone at any age however getting married is often reserved for when lovers become older and mature to handle what the union will bring.

     A young South African couple have caused quite a stir on social media after news of their marriage went viral.

     A young boy of 16 has decided to tie the knot with his 15-year-old girlfriend and his family are in full support of the union

     According to Daily Sun, the young man Siyacela Dlamuka, is set to walk down the aisle with his bride Thando Mathebula, on April 13, 2019.

     The excited groom-to-be revealed that he is very happy about his choice of bride because “she is different and special”. He also added tha…

Father In Custody For Killing 5 Year Old Son

Residents of Basale village in Endebess, Trans-Nzoia county woke up to the shocking news that a villager had strangled his five-year-old son.

     The man is being held at Endebess police station following the Friday night incident.

     The boy was a standard one pupil at Kibwoi primary school and the first born in the family.

     Neighbours said they heard some screams from the boy but thought he was being disciplined by his father.

    “I heard the boy screaming and crying and I thought he was being disciplined by his father. I was shocked to learn in the morning that he had been killed,” said a neighbour.

     The child’s mother was away when the incident happened.

     It was the boy’s father that alerted neighbours that his son had died after allegedly being attacked by unknown people while heading home from school, a theory residents refused to buy.

     The man was arrested after residents alerted police that he had killed his son and was trying to cover up the crime.

  …

"I'll sacrifice My Champions League Dream For Liverpool Fans" - Muhamed Salah

The Egypt international says his priority is Europe's top competition but he is desperate to deliver the Premier League for supporters.

     Mohamed Salah says he will "sacrifice" his Champions League dream if it means giving Liverpool supporters what they crave.

    The Anfield club are chasing glory on two fronts, with star striker Salah, 26, admitting Europe's elite competition is his priority over the Premier League .


nbsp;   With Liverpool heading into Wednesday's last-16 second leg clash with Bayern Munich with the tie poised at 0-0 and the club second in the Premier League a point behind leaders Manchester City , success in both competitions is a possibiscr

    While Salah acknowledges the Champions League is the most "prestigious competition", he knows Liverpool fans want a first title of the Premier League era more than anything.

    "I will be honest with you, the most prestigious competition for me is the Champions League," said Sa…

Lest We Forget 😭

Michele Mallin was a victim of a violent rape in 1985. The then 24 years old Texas Tech student was parking her car when she was approached by an African-American who asked for her help to jump start his car with cables. 
    When she said she didn't have any cables he reached in through the window opened the car door placing a knife to her neck he force her to the passenger seat and drove off. He drove to vacant field outside of town where he forced her to perform oral sex after which he then raped her. He then drove back after which he took $2 in cash from her, her watch and ring then left on foot. Mallin then immediately called the police, reported the crime and the investigation was under way.
    Mallin described the attacker to the police giving the details about his clothings (shirt and sandals) and also the fact that he smoked alot.
     The police said that it might have been the work of a serial rapist (“Tech rapist”) who was suspected of about four other rapes. Com…

The Trail Of Tears: Government-Approved Ethnic Cleansing That Removed 100,000 Native Americans From Their Ancestral Lands

Throughout the 1830s, President Andrew Jackson ordered the forced removal of tens of thousands of Native Americans from their homelands east of the Mississippi River. This perilous journey to designated lands in the west, known as the "Trail of Tears", was fraught with harsh winters, disease, and cruelty.
     The Trail of Tears refers to the perilous journey of the 'Five Civilized Tribes' of the Southeast who were forced from their ancestral homelands to a designated zone in the west.
    The name came to encompass the removal of all five tribes that occupied the southeastern United States. All tribes incurred thousands of deaths and all experienced the sorrow of being ousted from their ancestral homelands. Today, many historians view Jackson’s actions as nothing short of ethnic cleansing.
 The Policy Of Civilization
     For generations, the lands east of the Mississippi River had been the homeland of five tribal nations: the Cherokee, Creek, and Seminole in the so…

The Stomach-Turning History Of Rat Torture – Perhaps History’s Worst Way To Die

Humans have a long history of developing inventive ways to hurt each other. There’s seemingly no end to the horrifying torture devices that people have conceived. But one of the most terrifying methods of torture ever created doesn’t require a man-made device at all. Instead, it just requires a rat.
     There are a lot of bad ways to go, but rat torture may be the worst.
     Many people naturally feel a sense of fear and revulsion towards rats. And the animals will chew through nearly anything, including human flesh. And that makes them perfect tools for torture. Especially if the torturer knew how to use them.
     One of the most fiendish forms of rat torture involves placing a rat inside a half-cage and atop a restrained person’s abdomen. Then, the cage is slowly heated. Desperate to escape the heat, the rat begins to burrow through the only soft surface it can find: the victim’s flesh. With sharp claws and teeth, the rat quickly gnaws its way into the victim’s bowels, causi…